Toward unidirectional switches: 2-(2-Hydroxyphenyl)pyridine and 2-(2-methoxyphenyl)pyridine derivatives as pH-triggered pivots

• Christina Tepper and
• Gebhard Haberhauer

Beilstein J. Org. Chem. 2012, 8, 977–985, doi:10.3762/bjoc.8.110

• unidirectionally at the molecular level. If a 2-(2-methoxyphenyl)pyridine derivative is fixed to a chiral cyclopeptidic scaffold, a unidirectional progress of the rotation is achieved macroscopically. Keywords: CD spectroscopy; chirality; molecular modeling; molecular switches; unidirectional movements

• unidirectional movements of smaller parts thereof and which, thus, should be able to perform a physical task [2]. One important requirement for the construction of a molecular motor is that at least one movement of the motor proceeds unidirectionally. Such a unidirectional movement was already realized for